Coordinador: Dr. Raúl Carrillo Esper.
Coordinador: Dr. Martín de Jesús Sánchez Zúñiga .

Marco de Refetencia, Estrategias y Líneas de Acción

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Prevalence and impact of frailty on mortality in elderly ICU patients: a prospective, multicenter, observational study. 1. leflohic. Prevalence and impact of frailty on mortality in elderly ICU patients: a prospective, multicenter, observational study. 2018 Jul 25;:1–34.


Critically ill elderly patients (≥ 90 years): Clinical characteristics, outcome and financial implications 1. Le Borgne P, Maestraggi Q, Couraud S, Lefebvre F, Herbrecht J-E, Boivin A, et al. Critically ill elderly patients (≥ 90 years): Clinical characteristics, outcome and financial implications. Lazzeri C, editor. PLoS ONE. 2018 Jun 1;13(6):e0198360–12.


Situación funcional como factor independiente asociado con el mal pronóstico de pacientes ancianos ingresados en Cuidados Intensivos Revista Española de Geriatría y Gerontología, Corrected proof. doi:10.1016/j.regg.2017.08.002 1. Gordo F, Castro C, Torrejón I, Bartolomé S, Coca F, Abella A. Situación funcional como factor independiente asociado con el mal pronóstico de pacientes ancianos ingresados en Cuidados Intensivos. Revista Española de Geriatría y Gerontología. SEGG; 2018 Apr 16;:1–4.


Difference between elderly and non-elderly patients in using serum lactate level to predict mortality caused by sepsis in the emergency department 1. Cheng H-H, Chen F-C, Change M-W, Kung C-T, Cheng C-Y, Tsai T-C, et al. Difference between elderly and non-elderly patients in using serum lactate level to predict mortality caused by sepsis in the emergency department. Medicine. 2018 Mar;97(13):e0209–6.


Challenging decision: ICU admission of critically ill elderly solid tumor patients 1. Challenging decision: ICU admission of critically ill elderly solid tumor patients. 2017 Oct 30;:1–4.


Effect of Systematic Intensive Care Unit Triage on Long-term Mortality Among Critically Ill Elderly Patients in France 1. Guidet B, Leblanc G, Simon T, Woimant M, Quenot J-P, Ganansia O, et al. Effect of Systematic Intensive Care Unit Triage on Long-term Mortality Among Critically Ill Elderly Patients in France. JAMA. 2017 Oct 17;318(15):1450–10.


Effect of Systematic Intensive Care Unit Triage on Long-term Mortality Among Critically Ill Elderly Patients in France 1. Guidet B, Leblanc G, Simon T, Woimant M, Quenot J-P, Ganansia O, et al. Effect of Systematic Intensive Care Unit Triage on Long-term Mortality Among Critically Ill Elderly Patients in France. JAMA. 2017 Oct 17;318(15):1450–2.


The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (= 80 years) Intensive Care Medicine, doi:10.1007/s00134-017-4940-8 1. Flaatten H, Lange DW, Morandi A, Andersen FH, Artigas A, Bertolini G, et al. The impact of frailty on ICU and 30-day mortality and the level of care in very elderly patients (= 80 years). Intensive Care Med. Springer Berlin Heidelberg; 2017 Sep 20;:1–9.


Are we ever too old? 1. Muessig JM, Masyuk M, Nia AM, Franz M, Kabisch B, Kelm M, et al. Are we ever too old? Medicine. 2017 Sep;96(37):e7776–5.


Outcomes of very elderly (≥ 80 years) critical-ill patients in a medical intensive care unit of a tertiary hospital in Korea 1. Lee SH, Lee TW, Ju S, Yoo J-W, Lee SJ, Cho YJ, et al. Outcomes of very elderly (≥ 80 years) critical-ill patients in a medical intensive care unit of a tertiary hospital in Korea. Korean J Intern Med. 2017 Jul;32(4):675–81.


Geriatric patients in the ICU 1. Geriatric patients in the ICU. 2017 Jun 21;:1–3.


Long-Term Outcomes After ICU Admission Triage in Octogenarians 1. Andersen FH, Flaatten H, Klepstad P, Follestad T, Strand K, Krüger AJ, et al. Long-Term Outcomes After ICU Admission Triage in Octogenarians. Critical Care Medicine. 2017 Apr;45(4):e363–71.


The status of intensive care medicine research and a future agenda for very old patients in the ICU Intensive Care Medicine, doi:10.1007/s00134-017-4718-z 1. Flaatten H, Lange DW, Artigas A, Bin D, Moreno R, Christensen S, et al. The status of intensive care medicine research and a future agenda for very old patients in the ICU. Intensive Care Med. Springer Berlin Heidelberg; 2017 Feb 24;43(9):1–10.


Pulmonary arterial hypertension in critically ill elderly patients 1. Zhang Y, Xu F, Chu M, Bi L-Q. Pulmonary arterial hypertension in critically ill elderly patients. Pak J Med Sci. 2017 Feb 6;33(1):1–6.


A Comprehensive Multimorbidity Index for Predicting Mortality in Intensive Care Unit Patients 1. Min H, Avramovic S, Wojtusiak J, Khosla R, Fletcher RD, Alemi F, et al. A Comprehensive Multimorbidity Index for Predicting Mortality in Intensive Care Unit Patients. Journal of Palliative Medicine. 2017 Jan;20(1):35–41.


Age-related injury patterns in Spanish trauma ICU patients. Results from the RETRAUCI Advances in orthopaedic trauma in Spain 2016, (2016) S61-S65. doi:10.1016/S0020-1383(16)30608-8 1. Llompart-Pou JA, Chico-Fernández M, Sánchez-Casado M, Alberdi-Odriozola F, Guerrero-López F, Mayor-García MD, et al. Age-related injury patterns in Spanish trauma ICU patients. Results from the RETRAUCI. Advances in orthopaedic trauma in Spain 2016. Elsevier Masson SAS; 2016 Sep 1;47(Supplement 3):S61–5.


Very old patients urgently referred to the intensive care unit: long-term outcomes for admitted and declined patients 1. lnewlyn. Very old patients urgently referred to the intensive care unit: long-term outcomes for admitted and declined patients. 2016 Aug 16;:1–8.


Mortalidad y estado funcional al año de pacientes ancianos con ingreso prolongado en una unidad de cuidados intensivos 1. Pintado MC, Villa P, Luján J, Trascasa M, Molina R, González-García N, et al. Mortalidad y estado funcional al año de pacientes ancianos con ingreso prolongado en una unidad de cuidados intensivos. Medicina Intensiva. 2016 Jun;40(5):289–97.


Functional Status and Quality of Life in Elderly Intensive Care Unit Survivors 1. Villa P, Pintado M-C, Luján J, González-García N, Trascasa M, Molina R, et al. Functional Status and Quality of Life in Elderly Intensive Care Unit Survivors. J Am Geriatr Soc. 2016 Mar 21;64(3):536–42.


Is frailty a prognostic factor for critically ill elderly patients? Aging Clinical and Experimental Research, doi:10.1007/s40520-016-0557-y 1. Kizilarslanoglu MC, Civelek R, Kilic MK, Sumer F, Varan HD, Kara O, et al. Is frailty a prognostic factor for critically ill elderly patients? Aging Clinical and Experimental Research. Springer International Publishing; 2016 Mar 19;:1–9.


Are elderly patients' opinions sought before admission to an intensive care unit? Results of the ICE-CUB study 1. Le Guen J, Boumendil A, Guidet B, Corvol A, Saint-Jean O, Somme D. Are elderly patients' opinions sought before admission to an intensive care unit? Results of the ICE-CUB study. Age Ageing. 2016 Mar 3;45(2):303–9.


Clinical characteristics and outcome of very elderly patients ≥90 years in intensive care: a retrospective observational study Annals of Intensive Care, doi:10.1186/s13613-015-0097-1 1. Becker S, Müller J, Heer G, Braune S, Fuhrmann V, Kluge S. Clinical characteristics and outcome of very elderly patients ≥90 years in intensive care: a retrospective observational study. Annals of Intensive Care. Springer Paris; 2015 Dec 20;5(1):1–8.


Evaluation of long-term outcomes of very old patients admitted to intensive care: Survival, functional status, quality of life, and quality-adjusted life-years Journal of Critical Care, 30 (2015) 1150.e7-1150.e11. doi:10.1016/j.jcrc.2015.05.005 1. MD CF, MD CQ, MD CC, MD IA, PhD TC. Evaluation of long-term outcomes of very old patients admitted to intensive care: Survival, functional status, quality of life, and quality-adjusted life-years. Journal of Critical Care. Elsevier Inc; 2015 Oct 1;30(5):1150.e7–1150.e11.


Evaluation of long-term outcomes of very old patients admitted to intensive care: Survival, functional status, quality of life, and quality-adjusted life-years Journal of Critical Care, 30 (2015) 1150.e7-1150.e11. doi:10.1016/j.jcrc.2015.05.005 1. MD CF, MD CQ, MD CC, MD IA, PhD TC. Evaluation of long-term outcomes of very old patients admitted to intensive care: Survival, functional status, quality of life, and quality-adjusted life-years. Journal of Critical Care. Elsevier Inc; 2015 Oct 1;30(5):1150.e7–1150.e11.


Outcome of elderly patients who receive intensive care at a regional hospital in Hong Kong 1. Department of Intensive Care, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong, Shum HP, Chan KC, Wong HY, Yan WW. Outcome of elderly patients who receive intensive care at a regional hospital in Hong Kong. Hong Kong Med J. 2015 Sep 29;:1–9.


The very old ICU patient: a never-ending story Intensive Care Medicine, doi:10.1007/s00134-015-4052-2 1. Flaatten H, Garrouste-Orgeas M. The very old ICU patient: a never-ending story. Intensive Care Med. Springer Berlin Heidelberg; 2015 Sep 10;41(11):1996–8.


The very old ICU patient: a never-ending story Intensive Care Medicine, doi:10.1007/s00134-015-4052-2 1. Flaatten H, Garrouste-Orgeas M. The very old ICU patient: a never-ending story. Intensive Care Med. Springer Berlin Heidelberg; 2015 Sep 10;41(11):1996–8.


Prognostic factors associated with adverse outcome among critically ill elderly patients admitted to the intensive care unit 1. Orsini J, Butala A, Salomon S, Studer S, Gadhia S, Shamian B, et al. Prognostic factors associated with adverse outcome among critically ill elderly patients admitted to the intensive care unit. Geriatrics & Gerontology International. 2014 Sep 26;15(7):889–94.


Mortality in elderly ICU patients: a cohort study. BACKGROUND:The population is aging. We examined changes in the proportion of elderly (≥ 80 years) intensive care unit (ICU) patients during 2005-2011 and the association between age and mortality controlling for preexisting morbidity.


METHODS:Through the Danish National Patient Registry, we identified a cohort of 49,938 ICU admissions (47,596 patients) in Northern Denmark from 2005 to 2011. Patients were subdivided in age groups (15-49, 50-64, 65-79 and ≥ 80 years) and calendar year. We estimated 30-day and 31-365-day mortality and mortality rate ratios (MRRs), stratified by admission type (medical and elective/acute surgical patients). Mortality was compared between age groups adjusting for sex and preexisting morbidity using 50-64-year-olds as reference.


RESULTS:The proportion of elderly patients increased from 11.7% of all ICU patients in 2005 to 13.8% in 2011. Among the elderly, the 30-day mortality was 43.7% in medical, 39.6% in acute surgical, and 11.6% in elective surgical ICU patients. The corresponding adjusted 30-day MRRs compared with the 50-64-year-olds were 2.7 [95% confidence interval (CI) 2.5-3.0] in medical, 2.7 (95% CI 2.4-3.0) in acute surgical, and 5.2 (95% CI 4.1-6.6) in elective surgical ICU patients. The 31-365-day mortality among elderly patients was 25.4% in medical, 26.9% in acute, and 11.9% in elective surgical ICU patients, corresponding to adjusted MRRs of 2.5 (95% CI 2.1-2.9), 2.2 (95% CI 1.9-2.5), and 1.9 (95% CI 1.6-2.3), respectively.


CONCLUSIONS:During 2005-2011, there was an 18% increase in the proportion of elderly ICU patients. Advancing age is associated with increased mortality even after controlling for preexisting morbidity. 1. NIELSSON MS, CHRISTIANSEN CF, JOHANSEN MB, RASMUSSEN BS, TØNNESEN E, NØRGAARD M. Mortality in elderly ICU patients: a cohort study. Acta Anaesthesiol Scand. 2014 Jan;58(1):19–26.


Do elderly intensive care unit patients receive less intensive care treatment and have higher mortality? 1. ANDERSEN FH, KVÅLE R. Do elderly intensive care unit patients receive less intensive care treatment and have higher mortality? Acta Anaesthesiol Scand. 2012 Sep 28;56(10):1298–305.


ICU admission characteristics and mortality rates among elderly and very elderly patients 1. Fuchs L, Chronaki CE, Park S, Novack V, Baumfeld Y, Scott D, et al. ICU admission characteristics and mortality rates among elderly and very elderly patients. Intensive Care Med. 2012 Jul 14;38(10):1654–61.


Synergistic impact of low serum albumin on intensive care unit admission and high blood urea nitrogen during intensive care unit stay on post-intensive care unit mortality in critically ill elderly patients requiring mechanical ventilation 1. Pan S-W, Kao H-K, Yu W-K, Lien T-C, Chen Y-W, Wang J-H, et al. Synergistic impact of low serum albumin on intensive care unit admission and high blood urea nitrogen during intensive care unit stay on post-intensive care unit mortality in critically ill elderly patients requiring mechanical ventilation. Geriatrics & Gerontology International. 2012 Jun 4;13(1):107–15.


Development of demographics and outcome of very old critically ill patients admitted to intensive care units 1. Ihra GC, Lehberger J, Hochrieser H, Bauer P, Schmutz R, Metnitz B, et al. Development of demographics and outcome of very old critically ill patients admitted to intensive care units. Intensive Care Med. 2012 Feb 22;38(4):620–6.


muy viejos 1. muy viejos. 2011 Nov 25;:1–8.


Langzeitprognose alter Patienten nach intensiv- medizinischer Behandlung 1. Langzeitprognose alter Patienten nach intensiv- medizinischer Behandlung. 2011 Sep 19;:1–5.


untitled 1. untitled. 2011 Jun 17;:1–2.


Changes in health-related quality of life and factors predicting long-term outcomes in older adults admitted to intensive care units* 1. Khouli H, Astua A, Dombrowski W, Ahmad F, Homel P, Shapiro J, et al. Changes in health-related quality of life and factors predicting long-term outcomes in older adults admitted to intensive care units*. Critical Care Medicine. 2011 Apr;39(4):731–7.


Severe Sepsis and its Impact on Outcome in Elderly and Very Elderly Patients Admitted in Intensive Care Unit 1. Nasa P, Juneja D, Singh O, Dang R, Arora V. Severe Sepsis and its Impact on Outcome in Elderly and Very Elderly Patients Admitted in Intensive Care Unit. J Intensive Care Med. 2011 Feb 23;27(3):179–83.


La cuarta edad ante la medicina intensiva 1. Obón Azuara B, Gutiérrez Cía I, Sánchez Polo C. La cuarta edad ante la medicina intensiva. Medicina Intensiva. 2009 Dec;33(9):461–1.


El anciano en la unidad de cuidados intensivos 1. López-Soto A, Sacanella E, Pérez Castejón JM, Nicolás JM. El anciano en la unidad de cuidados intensivos. Revista Española de Geriatría y Gerontología. 2009 Jun;44:27–33.


Very old patients admitted to intensive care in Australia and New Zealand: a multi-centre cohort analysis 1. sufi01. Very old patients admitted to intensive care in Australia and New Zealand: a multi-centre cohort analysis. 2009 May 6;:1–14.


Analytic Reviews: Considerations in Caring for the Critically Ill Older Patient 1. Pisani MA. Analytic Reviews: Considerations in Caring for the Critically Ill Older Patient. J Intensive Care Med. 2nd ed. 2008 Dec 28;24(2):83–95.


Effect of Evidence-Based Feeding Guidelines on Mortality of Critically Ill Adults 1. Effect of Evidence-Based Feeding Guidelines on Mortality of Critically Ill Adults. 2008 Dec 8;:1–11.


Sex-and age-based differences in the delivery and outcomes of critical care 1. Fowler RA, Sabur N, Li P, Juurlink DN, Pinto R, Hladunewich MA, et al. Sex-and age-based differences in the delivery and outcomes of critical care. Canadian Medical Association Journal. 2007 Dec 4;177(12):1513–9.


The Ethical Challenge and the futile treatment in the older population admitted to the instensive care unit 1. Frezza EE, Squillario DM, Smith TJ. The Ethical Challenge and the futile treatment in the older population admitted to the instensive care unit. American Journal of Medical Quality. 2006 Sep 8;13(3):121–6.


Management of the critically ill geriatric patient 1. Marik PE. Management of the critically ill geriatric patient. Critical Care Medicine. 2006 Sep;34(Suppl):S176–82.


Decision-making process, outcome, and 1-year quality of life of octogenarians referred for intensive care unit admission 1. Garrouste-Orgeas M, Timsit J-F, Montuclard L, Colvez A, Gattolliat O, Philippart F, et al. Decision-making process, outcome, and 1-year quality of life of octogenarians referred for intensive care unit admission. Intensive Care Med. 2006 May 9;32(7):1045–51.


Prognosis of patients aged 80years and over admitted in medical intensive care unit 1. Boumendil A, Maury E, Reinhard I, Luquel L, Offenstadt G, Guidet B. Prognosis of patients aged 80years and over admitted in medical intensive care unit. Intensive Care Med. 2004 Apr 1;30(4):647–54.


Intensive care for very elderly patients: outcome and risk factors for in-hospital mortality 1. Intensive care for very elderly patients: outcome and risk factors for in-hospital mortality. 1999 Apr 21;:1–4.